“There have been enormous steps forward in technological aspects of genetics applied to colorectal cancer over the last 5 years. Surgeons have a central role in the overall management and advocacy of patients with colorectal cancer, including control of genetic risk in the patient as well as their relatives. Many patients may have a family history of the disease, or indeed are well aware of genetic implications of their diagnosis, especially if young age at onset. Furthermore, genetic factors are now impacting directly on downstream therapies through precision oncology. Hence, surgeons have a responsibility to be aware of recent advances in genetic analysis and the implications thereof. This lecture will provide an overview of diagnostic pathways as well as optimal management for risk reduction surgery in various high risk genetic disorders, as well as outlining the implications of germline and somatic testing and its integration into the management of patients as a whole in the concept of “mainstreaming” genetics in day-to-day surgical practice.”
How is all this genomics nonsense relevant to me as a surgeon?
Malcolm Dunlop, Goligher Keynote Lecture
Wednesday 11 July 2018, 10:00-10:30, Hall 1